4-     Systemic factors such as : endocrine deficiencies, deficiencies of iron, vitamin C&B , via lowering the resistance of the mucosa to trauma and  fungal infection

5-     Systemic disease as uncontrolled diabetic patient.

6-      After Radiation therapy.

7-     traumatic occlusion.

8-     poor fit denture.

Treatment of abused soft tissues:

1)      Rest of the denture supporting tissues.

2)      Occlusal correction of the old prosthesis.

3)      Good nutrition.

4)      Anti fungal therapy.

5)      Good oral hygiene.

6)      Improvement of denture fitness.

7)      Elimination of artificial relief and suction chamber in the maxillary complete denture.

      Uses of tissue conditioning material.

9)      Adequate relief of complete denture

10)        Treatment of oral manifestation of systemic diseases