September 19th, 2009 by admin
Cherubism
Etiology
• Autosomal-dominant, fibroblast/giant cell–containing
condition
• May be secondary to somatic mutation, mapping
to chromosome 4p16.3
• No associated metabolic or biochemical alterations noted
• Possible linkage/association with Noonan’s syndrome
Clinical Presentation
• Early signs in childhood
• Bilateral, symmetric enlargement of mandible
• Maxillary involvement less common and less prominent Read the rest of this entry »
September 19th, 2009 by admin
Amyloidosis
Etiology
• May be primary (idiopathic), secondary to systemic disease, or
familial
• Formation of a fibrillar protein deposited in soft tissues and
visceral organs with associated levels of dysfunction
Clinical Presentation Read the rest of this entry »
September 18th, 2009 by admin
Metastatic Cancer
Etiology
• Spread of a primary malignancy to the oral cavity structures or
jaws (usually from lung, breast, prostate, colon, kidney)
• Accounts for < 1% of oral malignancies
Clinical Presentation Read the rest of this entry »
September 18th, 2009 by admin
Ewing’s Sarcoma
Etiology
• Unknown
• Chromosomal translocations t(11;22), t(7;22), t(7;21) noted
• Gene rearrangement often noted, that is, (22;q12) and expression
of the MIC2 gene Read the rest of this entry »
September 18th, 2009 by admin
Etiology
• Usually indicates prematurely erupted deciduous teeth
Clinical Presentation
• Erupted teeth at birth
• Almost always are incisors
• 85% appear in mandible
Treatment
• If mobile, extraction
• Possible retention for functional, esthetic reasons
September 18th, 2009 by admin
Etiology
• A compulsive-eating disorder characterized by repeated
episodes of binge eating followed by vomiting or another form
of purging, including laxative abuse
• Cause may be biologic (neurometabolic disturbance), psychological
(societal pressure for extreme thinness), or combined Read the rest of this entry »
September 18th, 2009 by admin
Sarcoidosis
Etiology
• Unknown; granulomatous disease process
• May represent a systemic response to a single provoking agent;
mycobacteria has been suggested but not proven
• Possible role of genetic factors coupled with disordered reactions
to foreign antigens
Clinical Presentation Read the rest of this entry »
September 18th, 2009 by admin
Periapical Granuloma
Etiology
• A mass of inflamed granulation tissue
• Forms secondary to pulp necrosis of the associated tooth
• May develop following periapical abscess formation or may
form as pulpal death eventuates without abscess precursor
Clinical Presentation
• Usually asymptomatic Read the rest of this entry »
September 18th, 2009 by admin
Median Rhomboid Glossitis
Etiology
• A benign, inflammatory condition
• Often related to yeast colonization (erythematous candidiasis)
• Inflammatory process noted in response to overlying Candida
population
• Exact mechanism is unclear
Clinical Presentation
• Well-defined, asymptomatic erythematous patch on dorsum of
tongue
• Paramedian erythema, usually with focal atrophy of filiform
papillae
• Chronic forms may become multinodular. Read the rest of this entry »
September 18th, 2009 by admin
Garré’s Osteomyelitis
Etiology
• Chronic, low-grade, dentoalveolar infection
• Resultant bony inflammation extends to the periosteum, producing
a reduplication of the cortex (“onion skin” effect).
Clinical Presentation Read the rest of this entry »
